The addition of wild watermelon juice to melanin-producing cells (mouse melanoma cells) suppressed melanin production by the cells. This result suggests that wild watermelon juice might be effective in suppressing the occurrence of spots and dullness resulting from melanin production.
The growth of human skin fibroblasts was enhanced by the addition of wild watermelon juice to the culture medium, suggesting that wild watermelon juice activates skin fibroblasts. This effect might prevent wrinkle formation and the decline in skin fitness.
Growth of human epidermal keratinocytes was enhanced by the addition of wild watermelon juice, suggesting the possibility that wild watermelon juice activates human epidermal keratinocytes and stimulates their metabolism.
Wild watermelon can accumulate citrulline, a type of amino acid, which is effective in eliminating highly oxidative reactive oxygen named hydroxyl radWild watermelon can accumulate citrulline, a type of amino acid that is effective in eliminating hydroxyl radical, a highly oxidative reactive oxygen species. It has been demonstrated that the antioxidative activity of wild watermelon juice, i.e. its ability to prevent salicylic acid oxidationinduced by hydroxyl radicals, exceeds that of citrulline alone. This finding implies that wild watermelon contains, in addition to citrulline, another antioxidative compound that warrants further investigation.
Filters were immersed in water, glycerin, and wild watermelon juice, and their weights were measured after a certain wait time to calculate residual water content. The results showed that the residual water content of a filter that had been immersed in wild watermelon exceeded that of a filter immersed in glycerin, suggesting that the moisturizing effect of wild watermelon exceeds that of glycerin, a commonly used moisturizing component.