Atopic dermatitis was induced in mice that had been fed a diet containing a paramylon powder. The results showed that dermatitis scores and serum IgE (a protein produced in response to an immune reaction) levels decreased with the amount of ingested paramylon (Figs. a, b).
In addition, a clinical dermatological test was performed on 27 atopic dermatitis patients in their 10s to 60s. The levels of serum TARC and blood eosinophils, which are indicators of the severity of atopic dermatitis, significantly decreased after continuous ingestion of the paramylon powder for 2 months. The results of a questionnaire also showed clear improvement of the patient's quality of life (Figs. c, d, e). These results suggest that ingestion of a paramylon powder relieves the symptoms of atopic dermatitis to some extent.
Source: Sugiyama et al. J. Vet. Med. Sci. 72(6): 755-763, 2010
Atopic dermatitis is a kind of allergy that occurs on the skin and is typically associated with itching and inflammation. Guidelines of the Japanese Dermatological Association define atopic dermatitis as a condition that is characterized by eczema with itching, repeated improvement and worsening of symptoms, and an atopic disposition. Allergy is defined as an overactive immune response induced by an allergen.